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Carvedilol induces biased ß1 adrenergic receptor-nitric oxide synthase 3-cyclic guanylyl monophosphate signalling to promote cardiac contractility.
Wang, Qingtong; Wang, Ying; West, Toni M; Liu, Yongming; Reddy, Gopireddy R; Barbagallo, Federica; Xu, Bing; Shi, Qian; Deng, Bingqing; Wei, Wei; Xiang, Yang K.
Afiliação
  • Wang Q; The Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Hefei 230032, China.
  • Wang Y; Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • West TM; Department of Pharmacology, University of California at Davis, Davis, 95616 CA, USA.
  • Liu Y; Department of Pharmacology, University of California at Davis, Davis, 95616 CA, USA.
  • Reddy GR; Department of Pharmacology, University of California at Davis, Davis, 95616 CA, USA.
  • Barbagallo F; Department of Pharmacology, University of California at Davis, Davis, 95616 CA, USA.
  • Xu B; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China.
  • Shi Q; Department of Pharmacology, University of California at Davis, Davis, 95616 CA, USA.
  • Deng B; Department of Pharmacology, University of California at Davis, Davis, 95616 CA, USA.
  • Wei W; Department of Pharmacology, University of California at Davis, Davis, 95616 CA, USA.
  • Xiang YK; VA Northern California Health Care System, Mather, CA 95655, USA.
Cardiovasc Res ; 117(10): 2237-2251, 2021 08 29.
Article em En | MEDLINE | ID: mdl-32956449
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiotônicos / Receptores Adrenérgicos beta 1 / GMP Cíclico / Miócitos Cardíacos / Óxido Nítrico Sintase Tipo III / Antagonistas de Receptores Adrenérgicos alfa 1 / Carvedilol / Cardiopatias / Contração Miocárdica Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiotônicos / Receptores Adrenérgicos beta 1 / GMP Cíclico / Miócitos Cardíacos / Óxido Nítrico Sintase Tipo III / Antagonistas de Receptores Adrenérgicos alfa 1 / Carvedilol / Cardiopatias / Contração Miocárdica Idioma: En Ano de publicação: 2021 Tipo de documento: Article