A difunctional Pluronic®127-based in situ formed injectable thermogels as prolonged and controlled curcumin depot, fabrication, in vitro characterization and in vivo safety evaluation.

Khan, Samiullah; Akhtar, Naveed; Minhas, Muhammad Usman; Shah, Hassan; Khan, Kifayat Ullah; Thakur, Raghu Raj Singh

A difunctional Pluronic^®127-based in situ formed injectable thermogels as prolonged and controlled curcumin depot, fabrication, in vitro characterization and in vivo safety evaluation.

Khan, Samiullah; Akhtar, Naveed; Minhas, Muhammad Usman; Shah, Hassan; Khan, Kifayat Ullah; Thakur, Raghu Raj Singh.

Afiliação

Khan S; Department of Pharmacy, The University of Lahore, Gujrat Campus, Gujrat, Pakistan.
Akhtar N; Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Minhas MU; College of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Shah H; Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Khan KU; Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Thakur RRS; School of Pharmacy, Queen's University Belfast, Belfast, UK.

J Biomater Sci Polym Ed ; 32(3): 281-319, 2021 02.

Article em En | MEDLINE | ID: mdl-32976729

Assuntos

Curcumina; Poloxâmero; Curcumina/farmacologia; Liberação Controlada de Fármacos; Humanos; Hidrogéis; Transição de Fase; Espectroscopia de Infravermelho com Transformada de Fourier

Palavras-chave

MTT assay; Pluronic®127; Thermoresponsive depot; histopathology; poly(2-acrylamido-2-methylpropane sulfonic acid)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poloxâmero / Curcumina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poloxâmero / Curcumina Idioma: En Ano de publicação: 2021 Tipo de documento: Article