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Routine Early Antibiotic Use in SymptOmatic Preterm Neonates: A Pilot Randomized Controlled Trial.
Ruoss, J Lauren; Bazacliu, Catalina; Russell, Jordan T; Cruz, Diomel de la; Li, Nan; Gurka, Matthew J; Filipp, Stephanie L; Polin, Richard A; Triplett, Eric W; Neu, Josef.
Afiliação
  • Ruoss JL; Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL. Electronic address: lruoss@ufl.edu.
  • Bazacliu C; Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL.
  • Russell JT; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL.
  • Cruz D; Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL.
  • Li N; Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL.
  • Gurka MJ; Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL.
  • Filipp SL; Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL.
  • Polin RA; Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY.
  • Triplett EW; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL.
  • Neu J; Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL.
J Pediatr ; 229: 294-298.e3, 2021 02.
Article em En | MEDLINE | ID: mdl-32979383
ABSTRACT
We enrolled 98 infants (gestational age <33 weeks) in a pilot randomized trial of antibiotics vs no antibiotics; 55 were randomized (lower maternal infectious risk; symptoms expected for gestation). Adverse events did not differ significantly between the randomization arms. This trial establishes a framework for a larger multicentered trial.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Streptococcus agalactiae / Antibacterianos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Streptococcus agalactiae / Antibacterianos Idioma: En Ano de publicação: 2021 Tipo de documento: Article