Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-&#954;B signaling pathways.

Zhao, Xiaohui; Jiang, Sirong; Dong, Qi; Dang, Jun; Liu, Zenggeng; Han, Hongping; Tao, Yanduo; Yue, Huilan

Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-κB signaling pathways.

Zhao, Xiaohui; Jiang, Sirong; Dong, Qi; Dang, Jun; Liu, Zenggeng; Han, Hongping; Tao, Yanduo; Yue, Huilan.

Afiliação

Zhao X; Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS, Qinghai, 810008, China.
Jiang S; Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS, Qinghai, 810008, China.
Dong Q; Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS, Qinghai, 810008, China.
Dang J; Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS, Qinghai, 810008, China.
Liu Z; Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS, Qinghai, 810008, China.
Han H; Key Laboratory of Medicinal Animal and Plant Resources in Qinghai-Tibetan Plateau in Qinghai Province, Xining, 810008, China.
Tao Y; Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS, Qinghai, 810008, China. Electronic address: taoyanduo@163.com.
Yue H; Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS, Qinghai, 810008, China. Electronic address: hlyue@nwipb.cas.cn.

J Ethnopharmacol ; 266: 113402, 2021 Feb 10.

Article em En | MEDLINE | ID: mdl-32980481

Assuntos

Antirreumáticos/farmacologia; Artrite Experimental/tratamento farmacológico; Artrite Reumatoide/tratamento farmacológico; Glicosídeos Iridoides/farmacologia; Lamiaceae/química; Animais; Antirreumáticos/isolamento & purificação; Artrite Experimental/fisiopatologia; Artrite Reumatoide/fisiopatologia; Citocinas/metabolismo; Feminino; Inflamação/tratamento farmacológico; Inflamação/fisiopatologia; Glicosídeos Iridoides/isolamento & purificação; NF-kappa B/metabolismo; Osteoprotegerina/metabolismo; Ligante RANK/metabolismo; Ratos; Ratos Sprague-Dawley; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Adjuvant-induced arthritis; Iridoid glucosides; Lamiophlomis rotata (Benth.) kudo; OPG/RANKL/NF-κB signaling pathways

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Artrite Reumatoide / Antirreumáticos / Lamiaceae / Glicosídeos Iridoides Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google