Antimicrobial susceptibility of Staphylococcus species isolated from prosthetic joints with a focus on fluoroquinolone-resistance mechanisms.
Diagn Microbiol Infect Dis
; 99(1): 115173, 2021 Jan.
Article
em En
| MEDLINE
| ID: mdl-32992142
ABSTRACT
We investigated susceptibility to antimicrobials of 89 staphylococcal species from PJIs and analyzed fluoroquinolone (FQ)-resistance mechanisms. Staphylococcal isolates showed high resistance to oral antimicrobials, with the exception of TMP-STX and linezolid. The main mechanism of resistance to FQ was mutations in quinolone-resistance-determining-regions. Fifteen percent of Staphylococcus aureus overexpressed efflux-pump genes.
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Base de dados:
MEDLINE
Assunto principal:
Staphylococcus epidermidis
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Farmacorresistência Bacteriana
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Staphylococcus aureus Resistente à Meticilina
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Prótese Articular
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article