PartCrafter: find, generate and analyze BioParts.
Synth Biol (Oxf)
; 4(1): ysz014, 2019.
Article
em En
| MEDLINE
| ID: mdl-32995539
The field of Synthetic Biology is both practically and philosophically reliant on the idea of BioParts-concrete DNA sequences meant to represent discrete functionalities. While there are a number of software tools which allow users to design complex DNA sequences by stitching together BioParts or genetic features into genetic devices, there is a lack of tools assisting Synthetic Biologists in finding BioParts and in generating new ones. In practice, researchers often find BioParts in an ad hoc way. We present PartCrafter, a tool which extracts and aggregates genomic feature data in order to facilitate the search for new BioParts with specific functionalities. PartCrafter can also turn a genomic feature into a BioPart by packaging it according to any manufacturing standard, codon optimizing it for a new host, and removing forbidden sites. PartCrafter is available at partcrafter.com.
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MEDLINE
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Ano de publicação:
2019
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Article