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Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study.
Grachev, Igor D; Meyer, Philipp M; Becker, Georg A; Bronzel, Marcus; Marsteller, Doug; Pastino, Gina; Voges, Ole; Rabinovich, Laura; Knebel, Helena; Zientek, Franziska; Rullmann, Michael; Sattler, Bernhard; Patt, Marianne; Gerhards, Thilo; Strauss, Maria; Kluge, Andreas; Brust, Peter; Savola, Juha-Matti; Gordon, Mark F; Geva, Michal; Hesse, Swen; Barthel, Henryk; Hayden, Michael R; Sabri, Osama.
Afiliação
  • Grachev ID; Teva Branded Pharmaceutical Products R&D, Inc, Malvern, PA, 19355, USA.
  • Meyer PM; Guide Pharmaceutical Consulting, LLC, Millstone, NJ, 08535, USA.
  • Becker GA; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Bronzel M; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Marsteller D; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft mbH, Dresden, Germany.
  • Pastino G; Teva Branded Pharmaceutical Products R&D, Inc, Frazer, PA, 19355, USA.
  • Voges O; Teva Branded Pharmaceutical Products R&D, Inc, Frazer, PA, 19355, USA.
  • Rabinovich L; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft mbH, Dresden, Germany.
  • Knebel H; Teva Branded Pharmaceutical Products R&D, Inc, Frazer, PA, 19355, USA.
  • Zientek F; Teva Branded Pharmaceutical Products R&D, Inc, Frazer, PA, 19355, USA.
  • Rullmann M; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Sattler B; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Patt M; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Gerhards T; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Strauss M; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Kluge A; Department of Psychiatry and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.
  • Brust P; ABX-CRO Advanced Pharmaceutical Services Forschungsgesellschaft mbH, Dresden, Germany.
  • Savola JM; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Research Site Leipzig, Leipzig, Germany.
  • Gordon MF; Teva Branded Pharmaceutical Products R&D, Inc, Frazer, PA, 19355, USA.
  • Geva M; Teva Branded Pharmaceutical Products R&D, Inc, Frazer, PA, 19355, USA.
  • Hesse S; Prilenia Therapeutics Development Ltd., Herzliya, Israel.
  • Barthel H; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Hayden MR; Department of Nuclear Medicine, University of Leipzig Medical Center, Leipzig, Germany.
  • Sabri O; Prilenia Therapeutics Development Ltd., Herzliya, Israel.
Eur J Nucl Med Mol Imaging ; 48(4): 1103-1115, 2021 04.
Article em En | MEDLINE | ID: mdl-32995944
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dopamina / Doença de Huntington Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dopamina / Doença de Huntington Idioma: En Ano de publicação: 2021 Tipo de documento: Article