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A Functional Genomic Screen Identifies the Deubiquitinase USP11 as a Novel Transcriptional Regulator of ERα in Breast Cancer.
Dwane, Lisa; O'Connor, Aisling E; Das, Sudipto; Moran, Bruce; Mulrane, Laoighse; Pinto-Fernandez, Adan; Ward, Elspeth; Blümel, Anna M; Cavanagh, Brenton L; Mooney, Brian; Dirac, Annette M; Jirström, Karin; Kessler, Benedikt M; Ní Chonghaile, Tríona; Bernards, René; Gallagher, William M; O'Connor, Darran P.
Afiliação
  • Dwane L; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, Dublin, Ireland.
  • O'Connor AE; Cancer Biology and Therapeutics Laboratory, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
  • Das S; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, Dublin, Ireland.
  • Moran B; Cancer Biology and Therapeutics Laboratory, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
  • Mulrane L; Cancer Biology and Therapeutics Laboratory, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
  • Pinto-Fernandez A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Headington, Oxford, United Kingdom.
  • Ward E; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, Dublin, Ireland.
  • Blümel AM; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, Dublin, Ireland.
  • Cavanagh BL; Cellular and Molecular Imaging Core, Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Mooney B; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, Dublin, Ireland.
  • Dirac AM; Division of Molecular Carcinogenesis, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Jirström K; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
  • Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Headington, Oxford, United Kingdom.
  • Ní Chonghaile T; Department of Physiology and Medical Physics, Royal College of Surgeons Ireland, Dublin, Ireland.
  • Bernards R; Division of Molecular Carcinogenesis, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Gallagher WM; Cancer Biology and Therapeutics Laboratory, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
  • O'Connor DP; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, Dublin, Ireland. darranoconnor@rcsi.ie.
Cancer Res ; 80(22): 5076-5088, 2020 11 15.
Article em En | MEDLINE | ID: mdl-33004351
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tioléster Hidrolases / Neoplasias da Mama / Transativadores / Receptor alfa de Estrogênio / Enzimas Desubiquitinantes Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tioléster Hidrolases / Neoplasias da Mama / Transativadores / Receptor alfa de Estrogênio / Enzimas Desubiquitinantes Idioma: En Ano de publicação: 2020 Tipo de documento: Article