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Non-cytotoxic 1,2,3-triazole tethered fused heterocyclic ring derivatives display Tax protein inhibition and impair HTLV-1 infected cells.
Dos Santos, Daiane Fernanda; de Pilger, Denise Regina Bairros; Vandermeulen, Charlotte; Khouri, Ricardo; Mantoani, Susimaire Pedersoli; Nunes, Paulo Sérgio Gonçalves; de Andrade, Peterson; Carvalho, Ivone; Casseb, Jorge; Twizere, Jean-Claude; Willems, Luc; Freitas-Junior, Lucio; Kashima, Simone.
Afiliação
  • Dos Santos DF; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Regional Blood Center of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil. Electronic address: daiane-santos@alumni.usp.br.
  • de Pilger DRB; Federal University of São Paulo, São Paulo, São Paulo, Brazil; Department of Microbiology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil.
  • Vandermeulen C; Protein Signaling and Interactions (GIGA), University of Liège, Liège, Belgium.
  • Khouri R; Gonçalo Moniz Research Center (CPqGM), Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil.
  • Mantoani SP; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
  • Nunes PSG; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
  • de Andrade P; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
  • Carvalho I; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
  • Casseb J; Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, São Paulo, Brazil.
  • Twizere JC; Protein Signaling and Interactions (GIGA), University of Liège, Liège, Belgium.
  • Willems L; Molecular and Cellular Epigenetics (GIGA), University of Liège, Liège, Belgium.
  • Freitas-Junior L; Department of Microbiology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil.
  • Kashima S; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Regional Blood Center of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.
Bioorg Med Chem ; 28(22): 115746, 2020 11 15.
Article em En | MEDLINE | ID: mdl-33007558
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Triazóis / Vírus Linfotrópico T Tipo 1 Humano / Produtos do Gene tax / Compostos Heterocíclicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Triazóis / Vírus Linfotrópico T Tipo 1 Humano / Produtos do Gene tax / Compostos Heterocíclicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article