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A first-in-human phase 1 and pharmacological study of TAS-119, a novel selective Aurora A kinase inhibitor in patients with advanced solid tumours.
Robbrecht, Debbie G J; Lopez, Juanita; Calvo, Emiliano; He, Xiaomin; Hiroshi, Hirai; Soni, Nital; Cook, Natalie; Dowlati, Afshin; Fasolo, Angelica; Moreno, Victor; Eskens, Ferry A L M; de Bono, Johann S.
Afiliação
  • Robbrecht DGJ; Erasmus MC Cancer Institute, Rotterdam, the Netherlands. d.robbrecht@erasmusmc.nl.
  • Lopez J; The Royal Marsden and The Institute of Cancer Research, London, UK.
  • Calvo E; START Madrid-Centro Integral Oncológico Clara Campal, Hospital Madrid Norte Sanchinarro, Madrid, Spain.
  • He X; Taiho Oncology Inc, Princeton, NJ, USA.
  • Hiroshi H; Taiho Pharmaceutical Co., Ltd., Tokyo, Japan.
  • Soni N; Taiho Oncology Inc, Princeton, NJ, USA.
  • Cook N; Christie NHS Foundation Trust and the University of Manchester, Manchester, UK.
  • Dowlati A; UH Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA.
  • Fasolo A; Unit of New Drugs and Innovative Therapies Dept. Medical Oncology San Raffaele Hospital - Scientific Institute Via Olgettina, Milan, Italy.
  • Moreno V; START-Madrid-FJD, Hospital Fundacion Jimenez Diaz, Madrid, Spain.
  • Eskens FALM; Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • de Bono JS; The Royal Marsden and The Institute of Cancer Research, London, UK.
Br J Cancer ; 124(2): 391-398, 2021 01.
Article em En | MEDLINE | ID: mdl-33020594

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Aurora Quinase A / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Aurora Quinase A / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article