Short-term high-fat feeding induces a reversible net decrease in synaptic AMPA receptors in the hypothalamus.

Liu, Jianfeng; Dimitrov, Stoyan; Sawangjit, Anuck; Born, Jan; Ehrlich, Ingrid; Hallschmid, Manfred

Liu, Jianfeng; Dimitrov, Stoyan; Sawangjit, Anuck; Born, Jan; Ehrlich, Ingrid; Hallschmid, Manfred.

Afiliação

Liu J; Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany.
Dimitrov S; Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD), Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University Tübingen (IDM), Tübingen, Germ
Sawangjit A; Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany.
Born J; Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD), Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University Tübingen (IDM), Tübingen, Germ
Ehrlich I; Hertie Institute for Clinical Brain Research and Center for Integrative Neuroscience, University of Tübingen, Tübingen, Germany; Department of Neurobiology, Institute for Biomaterials and Biomolecular Systems, University of Stuttgart, Stuttgart, Germany.
Hallschmid M; Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD), Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University Tübingen (IDM), Tübingen, Germ

J Nutr Biochem ; 87: 108516, 2021 01.

Article em En | MEDLINE | ID: mdl-33022406

Assuntos

Dieta Hiperlipídica; Hipotálamo/fisiologia; Plasticidade Neuronal; Receptores de AMPA/metabolismo; Animais; Dieta Hiperlipídica/efeitos adversos; Ingestão de Energia; Masculino; Obesidade/etiologia; Obesidade/metabolismo; Fosforilação; Ratos Wistar; Receptores de AMPA/análise; Sinapses/fisiologia; Vigília

Palavras-chave

AMPA receptor signaling; Cortex; High-fat diet; Hypothalamus; Sleep/wakefulness; Synaptic plasticity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de AMPA / Dieta Hiperlipídica / Hipotálamo / Plasticidade Neuronal Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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