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Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases.
Lo, Michael K; Albariño, César G; Perry, Jason K; Chang, Silvia; Tchesnokov, Egor P; Guerrero, Lisa; Chakrabarti, Ayan; Shrivastava-Ranjan, Punya; Chatterjee, Payel; McMullan, Laura K; Martin, Ross; Jordan, Robert; Götte, Matthias; Montgomery, Joel M; Nichol, Stuart T; Flint, Mike; Porter, Danielle; Spiropoulou, Christina F.
Afiliação
  • Lo MK; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329; mko2@cdc.gov ccs8@cdc.gov.
  • Albariño CG; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • Perry JK; Gilead Sciences Inc., Foster City, CA 94404.
  • Chang S; Gilead Sciences Inc., Foster City, CA 94404.
  • Tchesnokov EP; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
  • Guerrero L; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
  • Chakrabarti A; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • Shrivastava-Ranjan P; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • Chatterjee P; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • McMullan LK; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • Martin R; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • Jordan R; Gilead Sciences Inc., Foster City, CA 94404.
  • Götte M; Gilead Sciences Inc., Foster City, CA 94404.
  • Montgomery JM; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
  • Nichol ST; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
  • Flint M; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • Porter D; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
  • Spiropoulou CF; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA 30329.
Proc Natl Acad Sci U S A ; 117(43): 26946-26954, 2020 10 27.
Article em En | MEDLINE | ID: mdl-33028676
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / RNA Polimerase Dependente de RNA / Monofosfato de Adenosina / Proteínas não Estruturais Virais / Alanina / Ebolavirus / Betacoronavirus Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / RNA Polimerase Dependente de RNA / Monofosfato de Adenosina / Proteínas não Estruturais Virais / Alanina / Ebolavirus / Betacoronavirus Idioma: En Ano de publicação: 2020 Tipo de documento: Article