Iron-mediated degradation of ribosomes under oxidative stress is attenuated by manganese.

Smethurst, Daniel G J; Kovalev, Nikolay; McKenzie, Erica R; Pestov, Dimitri G; Shcherbik, Natalia

Smethurst, Daniel G J; Kovalev, Nikolay; McKenzie, Erica R; Pestov, Dimitri G; Shcherbik, Natalia.

Afiliação

Smethurst DGJ; Department of Cell Biology and Neuroscience, Rowan University, School of Osteopathic Medicine, Stratford, New Jersey, USA.
Kovalev N; Department of Cell Biology and Neuroscience, Rowan University, School of Osteopathic Medicine, Stratford, New Jersey, USA.
McKenzie ER; Civil and Environmental Engineering Department, Temple University, Philadelphia, Pennsylvania, USA.
Pestov DG; Department of Cell Biology and Neuroscience, Rowan University, School of Osteopathic Medicine, Stratford, New Jersey, USA.
Shcherbik N; Department of Cell Biology and Neuroscience, Rowan University, School of Osteopathic Medicine, Stratford, New Jersey, USA. Electronic address: shcherna@rowan.edu.

J Biol Chem ; 295(50): 17200-17214, 2020 12 11.

Article em En | MEDLINE | ID: mdl-33040024

Assuntos

Ferro/metabolismo; Manganês/metabolismo; Estresse Oxidativo; Ribossomos/metabolismo; Saccharomyces cerevisiae/metabolismo; RNA Fúngico/genética; RNA Fúngico/metabolismo; RNA Ribossômico/genética; RNA Ribossômico/metabolismo; Ribossomos/genética; Saccharomyces cerevisiae/genética

Palavras-chave

RNA folding; cell viability; degradation of ribosomes; iron; iron metabolism; manganese; metals; oxidants; oxidative stress; ribosomal ribonucleic acid (rRNA); ribosome; ribosome structure; yeast

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribossomos / Saccharomyces cerevisiae / Estresse Oxidativo / Ferro / Manganês Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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