Role and mechanism of miR-187 in human cancer.

Peng, Weiwei; Sha, Huanhuan; Sun, Xun; Zou, Renrui; Zhu, Yue; Zhou, Guoren; Feng, Jifeng.

Afiliação

Peng W; The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research Nanjing, Jiangsu, China.
Sha H; The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research Nanjing, Jiangsu, China.
Sun X; The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research Nanjing, Jiangsu, China.
Zou R; The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research Nanjing, Jiangsu, China.
Zhu Y; The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research Nanjing, Jiangsu, China.
Zhou G; The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research Nanjing, Jiangsu, China.
Feng J; The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research Nanjing, Jiangsu, China.

Am J Transl Res ; 12(9): 4873-4884, 2020.

Article em En | MEDLINE | ID: mdl-33042395

ABSTRACT

MicroRNAs (miRNAs) are short non-coding RNAs, approximately 22 nucleotides in length, and involved in the post-transcriptional regulation of gene expression. MiRNAs play fundamental roles in many biological processes such as the development and progression of tumors. In this review, we briefly describe the expression of miR-187 in various types of cancer and discuss the role of miR-187 in cancer development and drug resistance. It is also possible to take miR-187 as an important indicator of diagnosis and prognosis of tumors.

Palavras-chave

MiR-187; biological processes; biomarker; cancers; drug resistance; prognosis

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article