Clinical characteristics and outcomes of bone marrow transplantation patients presenting to the ED of a tertiary care center.
Am J Emerg Med
; 46: 295-302, 2021 08.
Article
em En
| MEDLINE
| ID: mdl-33046319
ABSTRACT
BACKGROUND:
Bone marrow transplantation is a breakthrough in the world of hematology and oncology. In our region, there is scarce literature studying emergency department visits among BMT patients, as well as their predictors of mortality.OBJECTIVES:
This study aimed to assess the frequency, reasons, clinical characteristics and outcomes of patients presenting to the ED after a BMT, and to study the predictors of mortality in those patients. This study also compares those variables among the different types of BMT.METHODS:
This was a retrospective cohort study conducted on all adult patients who have completed a successful BMT and visited the ED.RESULTS:
Our study included 115 BMT patients, of whom 17.4% died. Those who died had a higher median number of ED visits than those who did not die. Around 36.5% presented with fever/chills with 29.6% diagnosed with pneumonia on discharge. We found that the odds of mortality were significantly higher among those who presented with dyspnea (p < .0005) and AMS (p = .023), among septic patients (p = .001), those who have undergone allogeneic BMT (p = .037), and those who were admitted to the ICU (p = .002). Moreover, the odds of mortality were significantly higher among hypotensive (p ≤0005) and tachycardic patients (p = .015).CONCLUSION:
In our study, we have shown that BMT patients visit the ED very frequently and have high risk of in-hospital mortality. Moreover, our study showed a significant association between mortality and patients with dyspnea, AMS, sepsis, allogeneic BMT type, ICU admission, hypotension and tachycardia.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Transplante de Medula Óssea
/
Serviço Hospitalar de Emergência
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article