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The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.
Sancho-Vaello, Enea; Gil-Carton, David; François, Patrice; Bonetti, Eve-Julie; Kreir, Mohamed; Pothula, Karunakar Reddy; Kleinekathöfer, Ulrich; Zeth, Kornelius.
Afiliação
  • Sancho-Vaello E; Unidad de Biofisica, Centro Mixto Consejo Superior de Investigaciones Cientificas-Universidad del País Vasco/Euskal Herriko Unibertsitatea (CSIC, UPV/EHU), Barrio Sarriena s/n, Leioa, Bizkaia, Spain.
  • Gil-Carton D; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • François P; Structural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia Edificio 800, 48160, Derio, Spain.
  • Bonetti EJ; Genomic Research Laboratory, Department of Medical Specialities, Geneva University Hospitals, University of Geneva, Genève, Switzerland.
  • Kreir M; Genomic Research Laboratory, Department of Medical Specialities, Geneva University Hospitals, University of Geneva, Genève, Switzerland.
  • Pothula KR; Nanion Technologies GmbH, Gabrielenstraße 9, 80636, Munich, Germany.
  • Kleinekathöfer U; Janssen Pharmaceutica NV, Janssen R&D, Nonclinical Safety, Beerse, Belgium.
  • Zeth K; Department of Physics and Earth Sciences, Jacobs University Bremen, Campus Ring 1, 28759, Bremen, Germany.
Sci Rep ; 10(1): 17356, 2020 10 15.
Article em En | MEDLINE | ID: mdl-33060695
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biopolímeros / Membrana Celular / Mimetismo Molecular / Peptídeos Catiônicos Antimicrobianos / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biopolímeros / Membrana Celular / Mimetismo Molecular / Peptídeos Catiônicos Antimicrobianos / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article