Tumor-associated macrophages: A promising target for a cancer immunotherapeutic strategy.

Zhang, Si-Yu; Song, Xin-Yu; Li, Yang; Ye, Lin-Lin; Zhou, Qiong; Yang, Wei-Bing

Zhang, Si-Yu; Song, Xin-Yu; Li, Yang; Ye, Lin-Lin; Zhou, Qiong; Yang, Wei-Bing.

Afiliação

Zhang SY; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China. Electronic address: 1784350239@qq.com.
Song XY; Department of Respiratory Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science, China Three Gorges University, Yichang, 443000, China. Electronic address: songxinyu@ctgu.edu.cn.
Li Y; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China. Electronic address: 1137474035@qq.com.
Ye LL; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China. Electronic address: 891024923@qq.com.
Zhou Q; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China. Electronic address: zhouqiongtj@126.com.
Yang WB; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China. Electronic address: 245449901@qq.com.

Pharmacol Res ; 161: 105111, 2020 11.

Article em En | MEDLINE | ID: mdl-33065284

Assuntos

Antineoplásicos/uso terapêutico; Imunoterapia; Ativação de Macrófagos/efeitos dos fármacos; Neoplasias/tratamento farmacológico; Macrófagos Associados a Tumor/efeitos dos fármacos; Animais; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Plasticidade Celular; Humanos; Terapia de Alvo Molecular; Neoplasias/imunologia; Neoplasias/metabolismo; Neoplasias/patologia; Fenótipo; Transdução de Sinais; Microambiente Tumoral; Macrófagos Associados a Tumor/imunologia; Macrófagos Associados a Tumor/metabolismo

Palavras-chave

Immunotherapy; Macrophage heterogeneity; PF-04136309 (PubChem CID:11192346); PLX3397 (pexidartinib) (PubChem CID:25151352); TMP195 (PubChem CID:67324851); Trabectedin (PubChem CID:108150); Tumor microenvironment; Tumor-associated macrophage; Zoledronate (PubChem CID:68740)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Macrófagos Associados a Tumor / Imunoterapia / Ativação de Macrófagos / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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