Selection and characterization of specific nanobody against neuropilin-1 for inhibition of angiogenesis.

Naderi, Shamsi; Roshan, Reyhaneh; Ghaderi, Hajarsadat; Behdani, Mahdi; Mahmoudi, Sara; Habibi-Anbouhi, Mahdi; Shokrgozar, Mohammad Ali; Kazemi-Lomedasht, Fatemeh

Naderi, Shamsi; Roshan, Reyhaneh; Ghaderi, Hajarsadat; Behdani, Mahdi; Mahmoudi, Sara; Habibi-Anbouhi, Mahdi; Shokrgozar, Mohammad Ali; Kazemi-Lomedasht, Fatemeh.

Afiliação

Naderi S; Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Roshan R; Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Ghaderi H; Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Behdani M; Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran. Electronic address: behdani@pasteur.ac.ir.
Mahmoudi S; Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Habibi-Anbouhi M; National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
Shokrgozar MA; National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
Kazemi-Lomedasht F; Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran. Electronic address: fa_kazemi@pasteur.ac.ir.

Mol Immunol ; 128: 56-63, 2020 12.

Article em En | MEDLINE | ID: mdl-33070092

Assuntos

Neovascularização Patológica/imunologia; Neuropilina-1/antagonistas & inibidores; Neuropilina-1/imunologia; Anticorpos de Domínio Único/imunologia; Linhagem Celular; Linhagem Celular Tumoral; Proliferação de Células/fisiologia; Células HEK293; Células Endoteliais da Veia Umbilical Humana; Humanos; Células MCF-7; Fator A de Crescimento do Endotélio Vascular/imunologia

Palavras-chave

Angiogenesis; NRP-1; Nanobody; VEGF

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neuropilina-1 / Anticorpos de Domínio Único / Neovascularização Patológica Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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