Alzheimer's Disease: Protective Effects of Mycobacterium vaccae, a Soil-Derived Mycobacterium with Anti-Inflammatory and Anti-Tubercular Properties, on the Proteomic Profiles of Plasma and Cerebrospinal Fluid in Rats.

Loupy, Kelsey M; Lee, Thomas; Zambrano, Cristian A; Elsayed, Ahmed I; D'Angelo, Heather M; Fonken, Laura K; Frank, Matthew G; Maier, Steven F; Lowry, Christopher A

Loupy, Kelsey M; Lee, Thomas; Zambrano, Cristian A; Elsayed, Ahmed I; D'Angelo, Heather M; Fonken, Laura K; Frank, Matthew G; Maier, Steven F; Lowry, Christopher A.

Afiliação

Loupy KM; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
Lee T; Central Analytical Laboratory and Mass Spectrometry Facility, Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.
Zambrano CA; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
Elsayed AI; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
D'Angelo HM; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.
Fonken LK; Division of Pharmacology and Toxicology, University of Texas at Austin, Austin, TX, USA.
Frank MG; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.
Maier SF; Center for Neuroscience, University of Colorado Boulder, Boulder, CO, USA.
Lowry CA; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.

J Alzheimers Dis ; 78(3): 965-987, 2020.

Article em En | MEDLINE | ID: mdl-33074227

Assuntos

Proteínas Sanguíneas/metabolismo; Proteínas do Líquido Cefalorraquidiano/metabolismo; Hipocampo/imunologia; Interleucina-4/imunologia; Metabolismo dos Lipídeos/imunologia; Mycobacteriaceae/imunologia; Proteômica; Vacinação; Doença de Alzheimer/imunologia; Animais; Hipocampo/metabolismo; Interleucina-4/genética; Proteínas; RNA Mensageiro/metabolismo; Ratos

Palavras-chave

Alzheimer's disease; ApoA-I; ApoC-II; cerebrospinal fluid; inflammation; lipid metabolism; mycobacteria; neurodegenerative disorder; neuroimmunomodulation; proteomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Sanguíneas / Proteínas do Líquido Cefalorraquidiano / Interleucina-4 / Vacinação / Proteômica / Metabolismo dos Lipídeos / Hipocampo / Mycobacteriaceae Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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