Multiple Introductions of Salmonella enterica Serovar Typhi H58 with Reduced Fluoroquinolone Susceptibility into Chile.

Maes, Mailis; Dyson, Zoe A; Higginson, Ellen E; Fernandez, Alda; Araya, Pamela; Tennant, Sharon M; Baker, Stephen; Lagos, Rosanna; Levine, Myron M; Hormazabal, Juan Carlos; Dougan, Gordon

Maes, Mailis; Dyson, Zoe A; Higginson, Ellen E; Fernandez, Alda; Araya, Pamela; Tennant, Sharon M; Baker, Stephen; Lagos, Rosanna; Levine, Myron M; Hormazabal, Juan Carlos; Dougan, Gordon.

Emerg Infect Dis ; 26(11): 2736-2740, 2020 11.

Article em En | MEDLINE | ID: mdl-33079054

ABSTRACT

ABSTRACT

Salmonella enterica serovar Typhi H58, an antimicrobial-resistant lineage, is globally disseminated but has not been reported in Latin America. Genomic analysis revealed 3 independent introductions of Salmonella Typhi H58 with reduced fluoroquinolone susceptibility into Chile. Our findings highlight the utility of enhanced genomic surveillance for typhoid fever in this region.

Assuntos

Antibacterianos/farmacologia; Farmacorresistência Bacteriana; Fluoroquinolonas/farmacologia; Salmonella typhi; Febre Tifoide; Chile/epidemiologia; Humanos; Testes de Sensibilidade Microbiana; Salmonella typhi/efeitos dos fármacos; Salmonella typhi/genética; Febre Tifoide/epidemiologia; Febre Tifoide/microbiologia

Palavras-chave

Chile; Salmonella Typhi H58; South America; antimicrobial resistance; bacteria; enteric diseases; fluoroquinolone resistance; genotyping; whole-genome sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Salmonella typhi / Febre Tifoide / Fluoroquinolonas / Farmacorresistência Bacteriana / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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