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The antidepressant-like activity of chiral xanthone derivatives may be mediated by 5-HT1A receptor and ß-arrestin signalling.
Salaciak, Kinga; Gluch-Lutwin, Monika; Siwek, Agata; Szafarz, Malgorzata; Kazek, Grzegorz; Bednarski, Marek; Nowinski, Leszek; Mitchell, Emma; Jastrzebska-Wiesek, Magdalena; Partyka, Anna; Wesolowska, Anna; Kolaczkowski, Marcin; Szkaradek, Natalia; Marona, Henryk; Sapa, Jacek; Pytka, Karolina.
Afiliação
  • Salaciak K; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
  • Gluch-Lutwin M; Department of Pharmacobiology, Jagiellonian University Medical College, Kraków, Poland.
  • Siwek A; Department of Pharmacobiology, Jagiellonian University Medical College, Kraków, Poland.
  • Szafarz M; Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
  • Kazek G; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
  • Bednarski M; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
  • Nowinski L; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
  • Mitchell E; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
  • Jastrzebska-Wiesek M; Department of Clinical Pharmacy, Jagiellonian University Medical College Kraków, Kraków, Poland.
  • Partyka A; Department of Clinical Pharmacy, Jagiellonian University Medical College Kraków, Kraków, Poland.
  • Wesolowska A; Department of Clinical Pharmacy, Jagiellonian University Medical College Kraków, Kraków, Poland.
  • Kolaczkowski M; Department of Medicinal Chemistry, Jagiellonian University Medical College Kraków, Kraków, Poland.
  • Szkaradek N; Department of Bioorganic Chemistry, Jagiellonian University Medical College, Krakow, Poland.
  • Marona H; Department of Bioorganic Chemistry, Jagiellonian University Medical College, Krakow, Poland.
  • Sapa J; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
  • Pytka K; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
J Psychopharmacol ; 34(12): 1431-1442, 2020 12.
Article em En | MEDLINE | ID: mdl-33103555
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Xantonas / Receptor 5-HT1A de Serotonina / Beta-Arrestinas / Antidepressivos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Xantonas / Receptor 5-HT1A de Serotonina / Beta-Arrestinas / Antidepressivos Idioma: En Ano de publicação: 2020 Tipo de documento: Article