What are we missing? Three cases of severe COVID-19 pneumonia with negative testing.
SAGE Open Med Case Rep
; 8: 2050313X20965410, 2020.
Article
em En
| MEDLINE
| ID: mdl-33117540
ABSTRACT
The COVID-19 pandemic has drastically affected health care systems globally. Reverse transcriptase-polymerase chain reaction is currently the preferred method of detecting COVID-19; however, sensitivity of this test remains questionable. Incidental transmission and potential harm to infected individuals are some consequences of the failure to identify high-risk patients. We report three cases of symptomatic patients that required intensive care management with labs and imaging consistent with COVID-19 with initial false-negative reverse transcriptase-polymerase chain reaction testing. Improper sampling, viral load, and manufacturer variances of tests all contribute to reduced sensitivity. A clinical diagnosis should supplant such cases.
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MEDLINE
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En
Ano de publicação:
2020
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Article