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Somatic HLA Class I Loss Is a Widespread Mechanism of Immune Evasion Which Refines the Use of Tumor Mutational Burden as a Biomarker of Checkpoint Inhibitor Response.
Montesion, Meagan; Murugesan, Karthikeyan; Jin, Dexter X; Sharaf, Radwa; Sanchez, Nora; Guria, Ameet; Minker, Max; Li, Gerald; Fisher, Virginia; Sokol, Ethan S; Pavlick, Dean C; Moore, Jay A; Braly, Alan; Singal, Gaurav; Fabrizio, David; Comment, Leah A; Rizvi, Naiyer A; Alexander, Brian M; Frampton, Garrett M; Hegde, Priti S; Albacker, Lee A.
Afiliação
  • Montesion M; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Murugesan K; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Jin DX; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Sharaf R; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Sanchez N; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Guria A; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Minker M; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Li G; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Fisher V; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Sokol ES; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Pavlick DC; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Moore JA; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Braly A; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Singal G; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Fabrizio D; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Comment LA; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Rizvi NA; Columbia University Irving Medical Center, New York, New York.
  • Alexander BM; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Frampton GM; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Hegde PS; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Albacker LA; Foundation Medicine, Inc., Cambridge, Massachusetts. lalbacker@foundationmedicine.com.
Cancer Discov ; 11(2): 282-292, 2021 02.
Article em En | MEDLINE | ID: mdl-33127846
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Checkpoint Imunológico / Antígenos HLA / Neoplasias Pulmonares Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Inibidores de Checkpoint Imunológico / Antígenos HLA / Neoplasias Pulmonares Idioma: En Ano de publicação: 2021 Tipo de documento: Article