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Mechanistic study of preparation of drug/polymer/surfactant ternary hot extrudates to obtain small and stable drug nanocrystal suspensions.
Omagari, Katsuhiko; Ueda, Keisuke; Zhijing, Zhao; Higashi, Kenjirou; Inoue, Motoki; Fukami, Toshiro; Moribe, Kunikazu.
Afiliação
  • Omagari K; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
  • Ueda K; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
  • Zhijing Z; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
  • Higashi K; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
  • Inoue M; Department of Molecular Pharmaceutics, Meiji Pharmaceutical University, Kiyose, 2-522-1 Noshino, Kiyose-shi, Tokyo 204-8588, Japan.
  • Fukami T; Department of Molecular Pharmaceutics, Meiji Pharmaceutical University, Kiyose, 2-522-1 Noshino, Kiyose-shi, Tokyo 204-8588, Japan.
  • Moribe K; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan. Electronic address: moribe@faculty.chiba-u.jp.
Int J Pharm ; 591: 120003, 2020 Dec 15.
Article em En | MEDLINE | ID: mdl-33132150
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tensoativos / Nanopartículas Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tensoativos / Nanopartículas Idioma: En Ano de publicação: 2020 Tipo de documento: Article