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Sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring.
Venkatratnam, Abhishek; Douillet, Christelle; Topping, Brent C; Shi, Qing; Addo, Kezia A; Ideraabdullah, Folami Y; Fry, Rebecca C; Styblo, Miroslav.
Afiliação
  • Venkatratnam A; Department of Nutrition, CB# 7461, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7461, USA.
  • Douillet C; Department of Environmental Sciences and Engineering, CB#7431, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7431, USA.
  • Topping BC; Department of Nutrition, CB# 7461, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7461, USA.
  • Shi Q; Department of Environmental Sciences and Engineering, CB#7431, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7431, USA.
  • Addo KA; Department of Nutrition, CB# 7461, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7461, USA.
  • Ideraabdullah FY; Department of Environmental Sciences and Engineering, CB#7431, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7431, USA.
  • Fry RC; Department of Nutrition, CB# 7461, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7461, USA.
  • Styblo M; Department of Genetics, CB#7264, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7264, USA.
Arch Toxicol ; 95(2): 473-488, 2021 02.
Article em En | MEDLINE | ID: mdl-33145626

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Ilhotas Pancreáticas / Arsenitos / Diabetes Mellitus / Transcriptoma / Células Germinativas Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Ilhotas Pancreáticas / Arsenitos / Diabetes Mellitus / Transcriptoma / Células Germinativas Idioma: En Ano de publicação: 2021 Tipo de documento: Article