Activation of toll like receptor 4 (TLR4) promotes cardiomyocyte apoptosis through SIRT2 dependent p53 deacetylation.

Katare, Parmeshwar Bajirao; Nizami, Hina Lateef; Paramesha, Bugga; Dinda, Amit K; Banerjee, Sanjay K

Katare, Parmeshwar Bajirao; Nizami, Hina Lateef; Paramesha, Bugga; Dinda, Amit K; Banerjee, Sanjay K.

Afiliação

Katare PB; Drug Discovery Research Centre (DDRC), Translational Health Science and Technology Institute (THSTI), Faridabad, Haryana, 121001, India.
Nizami HL; Drug Discovery Research Centre (DDRC), Translational Health Science and Technology Institute (THSTI), Faridabad, Haryana, 121001, India.
Paramesha B; Drug Discovery Research Centre (DDRC), Translational Health Science and Technology Institute (THSTI), Faridabad, Haryana, 121001, India.
Dinda AK; Department of Pathology, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi, 110029, India.
Banerjee SK; Drug Discovery Research Centre (DDRC), Translational Health Science and Technology Institute (THSTI), Faridabad, Haryana, 121001, India. skbanerjee@thsti.res.in.

Sci Rep ; 10(1): 19232, 2020 11 06.

Article em En | MEDLINE | ID: mdl-33159115

Assuntos

Apoptose; Miócitos Cardíacos/metabolismo; Sirtuína 2/metabolismo; Receptor 4 Toll-Like/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Acetilação; Animais; Linhagem Celular; Lipopolissacarídeos/farmacologia; Masculino; Ratos; Ratos Sprague-Dawley

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Apoptose / Miócitos Cardíacos / Receptor 4 Toll-Like / Sirtuína 2 Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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