The prevalence of self-reported medical comorbidities in patients with vulvar lichen sclerosus: A single-center retrospective study.
Int J Gynaecol Obstet
; 153(2): 340-343, 2021 May.
Article
em En
| MEDLINE
| ID: mdl-33184843
ABSTRACT
OBJECTIVE:
To compare the demographics and self-reported medical comorbidities of patients with vulvar lichen sclerosus (VLS) with those of women with other vulvar conditions.METHODS:
Intake questionnaires for patients presenting to the University of Michigan Center for Vulvar Diseases between 1996 and 2019 were entered into a de-identified database (n = 1983). Responses to questions about thyroid disease, urinary symptoms and signs, gastrointestinal conditions, and pain conditions were collected.RESULTS:
A total of 1983 women, including 865 patients with VLS and 1118 patients without VLS were enrolled. Pearson's χ2 analysis showed that age, hypertension, anorectal fissures, peptic ulcer disease/gastroesophageal reflux disease, urinary incontinence, fibromyalgia, thyroid disease, kidney problems, liver problems, and cancer were significantly associated with VLS when compared between the VLS and non-VLS groups (P < 0.01). However, multiple regression analysis demonstrated that only age, thyroid disease, and anorectal fissures were strongly associated with VLS (P < 0.01).CONCLUSION:
Increasing age, thyroid disease, and anorectal fissures were significantly associated with VLS. The association between anorectal fissures and VLS likely represents a sequela of the disease rather than a true comorbidity.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Líquen Escleroso Vulvar
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article