Cutaneous follicle center lymphomas with plasmacytic differentiation.

Skala, Stephanie L; Harms, Paul W; Fullen, Douglas R; Brown, Noah A; Tejasvi, Trilokraj; Wilcox, Ryan A; Boyer, Daniel F; Hristov, Alexandra C

Skala, Stephanie L; Harms, Paul W; Fullen, Douglas R; Brown, Noah A; Tejasvi, Trilokraj; Wilcox, Ryan A; Boyer, Daniel F; Hristov, Alexandra C.

Afiliação

Skala SL; Department of Pathology, Michigan Medicine, Ann Arbor, Michigan, USA.
Harms PW; Department of Pathology, Michigan Medicine, Ann Arbor, Michigan, USA.
Fullen DR; Department of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
Brown NA; Department of Pathology, Michigan Medicine, Ann Arbor, Michigan, USA.
Tejasvi T; Department of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
Wilcox RA; Department of Pathology, Michigan Medicine, Ann Arbor, Michigan, USA.
Boyer DF; Department of Dermatology, Michigan Medicine, Ann Arbor, Michigan, USA.
Hristov AC; Department of Internal Medicine, Division of Hematology and Oncology, Michigan Medicine, Ann Arbor, Michigan, USA.

J Cutan Pathol ; 48(5): 632-636, 2021 May.

Article em En | MEDLINE | ID: mdl-33184902

ABSTRACT

ABSTRACT

Follicle center lymphomas, including primary cutaneous follicle center lymphoma (PCFCL), may rarely show plasmacytic differentiation. Such cases can pose a diagnostic challenge and can be mistaken for other lymphomas that more commonly include plasma cells. Here, we report four cases of PCFCL and one case of systemic follicular lymphoma involving the skin with associated monotypic plasma cells, including the clinical, morphologic and immunophenotypic features.

Assuntos

Cadeias kappa de Imunoglobulina/metabolismo; Linfoma de Células B/diagnóstico; Linfoma Folicular/diagnóstico; Plasmócitos/patologia; Neoplasias Cutâneas/patologia; Adulto; Idoso; Biópsia; Diferenciação Celular; Feminino; Humanos; Cadeias lambda de Imunoglobulina/metabolismo; Imunofenotipagem/métodos; Linfoma de Células B/patologia; Linfoma Folicular/cirurgia; Linfoma Folicular/ultraestrutura; Masculino; Pessoa de Meia-Idade; Plasmócitos/metabolismo; Resultado do Tratamento

Palavras-chave

cutaneous B-cell lymphoma; light chain restriction; plasmacytic differentiation; primary cutaneous follicle center lymphoma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmócitos / Neoplasias Cutâneas / Linfoma de Células B / Linfoma Folicular / Cadeias kappa de Imunoglobulina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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