Acute-on-chronic liver failure: Definitions, pathophysiology and principles of treatment.

Zaccherini, Giacomo; Weiss, Emmanuel; Moreau, Richard.

Afiliação

Zaccherini G; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Weiss E; European Foundation for the Study of Chronic Liver Failure (EF-CLIF), Barcelona, Spain.
Moreau R; European Foundation for the Study of Chronic Liver Failure (EF-CLIF), Barcelona, Spain.

JHEP Rep ; 3(1): 100176, 2021 Feb.

Article em En | MEDLINE | ID: mdl-33205036

Palavras-chave

AARC, APASL ACLF Research Consortium; ACLF, acute-on-chronic liver failure; AKI, acute kidney injury; APASL, Asian Pacific Association for the Study of the Liver; Acute decompensation; Bacterial infections; Bacterial translocation; CLIF, Chronic Liver Failure-Consortium; COSSH, Chinese Group on the Study of Severe Hepatitis; DAMPs, damage-associated molecular patterns; EASL, European Association for the Study of the Liver - Chronic Liver; ER, endoplasmic reticulum; HMGB1, high mobility group box 1; ICU, intensive care unit; INR, international normalised ratio; Immunopathology; Inflammatory response; MELD, model for end-stage liver disease; Metabolism; Multiorgan failure; NACSELD, North American Consortium for the Study of End-stage Liver Disease; NO, nitric oxide; OF, organ failure; PAMPs, pathogen-associated molecular patterns; PRR, pattern-recognition receptors; Sterile inflammation; TLR, Toll-like receptor; UNOS, United Network for Organ Sharing

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article