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Intranasal delivery of interferon-ß-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy.
González, Luis F; Acuña, Eric; Arellano, Gabriel; Morales, Paola; Sotomayor, Paula; Oyarzun-Ampuero, Felipe; Naves, Rodrigo.
Afiliação
  • González LF; Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Acuña E; Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Arellano G; Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Morales P; Molecular and Clinical Pharmacology Program, Institute of Biomedical Sciences and Department of Neuroscience, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
  • Sotomayor P; Center for Integrative Medicine and Innovative Science, Universidad Andrés Bello, Santiago, Chile.
  • Oyarzun-Ampuero F; Departamento de Ciencias y Tecnología Farmacéuticas, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), Santiago, Chile. Electronic address: foyarzuna@ciq.uchile.cl.
  • Naves R; Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile. Electronic address: rodrigonaves@uchile.cl.
J Control Release ; 331: 443-459, 2021 03 10.
Article em En | MEDLINE | ID: mdl-33220325
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encefalomielite Autoimune Experimental / Nanopartículas / Esclerose Múltipla Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encefalomielite Autoimune Experimental / Nanopartículas / Esclerose Múltipla Idioma: En Ano de publicação: 2021 Tipo de documento: Article