UBE2C mRNA expression controlled by miR-300 and HuR determines its oncogenic role in gastric cancer.

Wang, Ying; Huang, Feifei; Liu, Ming; Zhao, Quan

Wang, Ying; Huang, Feifei; Liu, Ming; Zhao, Quan.

Afiliação

Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Center for Translational Medicine, School of Life Sciences, Nanjing University, Nanjing, 210000, China; Department of Urology, Univ
Huang F; State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Center for Translational Medicine, School of Life Sciences, Nanjing University, Nanjing, 210000, China.
Liu M; State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Center for Translational Medicine, School of Life Sciences, Nanjing University, Nanjing, 210000, China.
Zhao Q; State Key Laboratory of Pharmaceutical Biotechnology, Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, China-Australia Center for Translational Medicine, School of Life Sciences, Nanjing University, Nanjing, 210000, China. Electronic address: qzhao@n

Biochem Biophys Res Commun ; 534: 597-603, 2021 01 01.

Article em En | MEDLINE | ID: mdl-33223052

Assuntos

Adenocarcinoma/genética; Adenocarcinoma/metabolismo; Proteína Semelhante a ELAV 1/metabolismo; MicroRNAs/genética; Neoplasias Gástricas/genética; Neoplasias Gástricas/metabolismo; Enzimas de Conjugação de Ubiquitina/genética; Adenocarcinoma/patologia; Carcinogênese/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células/genética; DNA de Neoplasias/biossíntese; Progressão da Doença; Regulação Neoplásica da Expressão Gênica; Inativação Gênica; Humanos; Oncogenes; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; RNA Neoplásico/genética; RNA Neoplásico/metabolismo; Neoplasias Gástricas/patologia; Enzimas de Conjugação de Ubiquitina/antagonistas & inibidores

Palavras-chave

Gastric cancer; HuR; UBE2C; mRNA expression; miR-300

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Adenocarcinoma / MicroRNAs / Enzimas de Conjugação de Ubiquitina / Proteína Semelhante a ELAV 1 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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