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Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Abrams, Rachel P M; Yasgar, Adam; Teramoto, Tadahisa; Lee, Myoung-Hwa; Dorjsuren, Dorjbal; Eastman, Richard T; Malik, Nasir; Zakharov, Alexey V; Li, Wenxue; Bachani, Muzna; Brimacombe, Kyle; Steiner, Joseph P; Hall, Matthew D; Balasubramanian, Anuradha; Jadhav, Ajit; Padmanabhan, Radhakrishnan; Simeonov, Anton; Nath, Avindra.
Afiliação
  • Abrams RPM; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Yasgar A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850.
  • Teramoto T; Department of Microbiology and Immunology, Georgetown University, Washington, DC 20057.
  • Lee MH; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Dorjsuren D; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850.
  • Eastman RT; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850.
  • Malik N; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Zakharov AV; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850.
  • Li W; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Bachani M; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Brimacombe K; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850.
  • Steiner JP; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850.
  • Balasubramanian A; Department of Microbiology and Immunology, Georgetown University, Washington, DC 20057.
  • Jadhav A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850.
  • Padmanabhan R; Department of Microbiology and Immunology, Georgetown University, Washington, DC 20057 rp55@georgetown.edu asimeono@mail.nih.gov natha@ninds.nih.gov.
  • Simeonov A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850; rp55@georgetown.edu asimeono@mail.nih.gov natha@ninds.nih.gov.
  • Nath A; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892; rp55@georgetown.edu asimeono@mail.nih.gov natha@ninds.nih.gov.
Proc Natl Acad Sci U S A ; 117(49): 31365-31375, 2020 12 08.
Article em En | MEDLINE | ID: mdl-33229545
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores de Proteases / Avaliação Pré-Clínica de Medicamentos / Ensaios de Triagem em Larga Escala / Zika virus Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Inibidores de Proteases / Avaliação Pré-Clínica de Medicamentos / Ensaios de Triagem em Larga Escala / Zika virus Idioma: En Ano de publicação: 2020 Tipo de documento: Article