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Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
la Marca, Giancarlo; Barp, Jacopo; Frenos, Stefano; Mugelli, Alessandro; Galli, Luisa; Calistri, Elisa; Biasucci, Giacomo; De Masi, Salvatore; Guerrini, Renzo.
Afiliação
  • la Marca G; Newborn Screening, Biochemistry and Pharmacology Laboratory, Meyer Children's University Hospital, Florence, Italy; Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy. Electronic address: giancarlo.lamarca@meyer.it.
  • Barp J; Gastroenterology and Nutrition Unit, Meyer Children's University Hospital, Florence, Italy.
  • Frenos S; Department of Haematology-Oncology: BMT Unit, Meyer Children's University Hospital, Florence, Italy.
  • Mugelli A; Section of Pharmacology and Toxicology, Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
  • Galli L; Infectious Diseases Unit, Meyer Children's University Hospital, Florence, Italy; Department of Health Sciences, University of Florence, Italy.
  • Calistri E; Department of Health Sciences, University of Florence, Italy; Immunology Unit, Meyer Children's University Hospital, Florence, Italy.
  • Biasucci G; Pediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, Piacenza, Italy.
  • De Masi S; Clinical Trial Office, Meyer Children's University Hospital, Florence, Italy.
  • Guerrini R; Section of Pharmacology and Toxicology, Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; Neurology, Neurogenetics and Neurobiology Unit and Laboratories, Meyer Children's University Hospital, Florence, Italy.
Life Sci ; 265: 118801, 2021 Jan 15.
Article em En | MEDLINE | ID: mdl-33232690
ABSTRACT

BACKGROUND:

The emergence of SARS-CoV-2 pandemic has upset health systems around the world and caused immeasurable losses and costs. Until a vaccine will become available, the recommended prevention measures remain physical distancing and enhanced hygiene. METHODS AND

FINDINGS:

The proteic structure external to the virus is the main target that may eventually lead to reduce or block its replication in the upper airways. We developed a protocol based of repeated steam inhalation cycles aimed at reducing the risk of progression to full blown infection if performed soon after contagion. The protocol has been used in a single-center open label trial on ten infected asymptomatic or pauci-symptomatic health care professionals.

CONCLUSIONS:

The promising results we obtained with this easily accessible, non-invasive and inexpensive procedure should prompt controlled trials.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vapor / SARS-CoV-2 / COVID-19 / Temperatura Alta Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vapor / SARS-CoV-2 / COVID-19 / Temperatura Alta Idioma: En Ano de publicação: 2021 Tipo de documento: Article