A multifunctional CeO<sub>2</sub>@SiO<sub>2</sub>-PEG nanoparticle carrier for delivery of food derived proanthocyanidin and curcumin as effective antioxidant, neuroprotective and anticancer agent.

Chen, Zhongqin; Xu, Leilei; Gao, Xudong; Wang, Chunli; Li, Ruilin; Xu, Jun; Zhang, Min; Panichayupakaranant, Pharkphoom; Chen, Haixia

A multifunctional CeO₂@SiO₂-PEG nanoparticle carrier for delivery of food derived proanthocyanidin and curcumin as effective antioxidant, neuroprotective and anticancer agent.

Chen, Zhongqin; Xu, Leilei; Gao, Xudong; Wang, Chunli; Li, Ruilin; Xu, Jun; Zhang, Min; Panichayupakaranant, Pharkphoom; Chen, Haixia.

Afiliação

Chen Z; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Xu L; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Gao X; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Wang C; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Li R; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Xu J; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Zhang M; Tianjin Agricultural University, Tianjin 300384, PR China; State Key Laboratory of Nutrition and Safety, Tianjin University of Science & Technology, Tianjin 300457, PR China.
Panichayupakaranant P; Phytomedicine and Pharmaceutical Biotechnology Excellence Center, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, Songkhla 90112, Thailand.
Chen H; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China. Electronic address: chenhx@tju.edu.cn.

Food Res Int ; 137: 109674, 2020 11.

Article em En | MEDLINE | ID: mdl-33233251

Assuntos

Antineoplásicos; Curcumina; Nanopartículas; Proantocianidinas; Antioxidantes/farmacologia; Curcumina/farmacologia; Portadores de Fármacos; Células HeLa; Humanos; Dióxido de Silício

Palavras-chave

Acetylthiocholine Iodide (PubChem CID: 74629); Ammonia aqueous (PubChem CID: 14923); Ammonium Carbonate (PubChem CID: 24660); Anticancer activity; Antioxidant activity; Cerium Nitrate Hexahydrate (PubChem CID: 16211466); Cerium oxide (PubChem CID: 73963); Curcumin; Curcumin (PubChem CID: 969516); Multifunctional nanoparticle; Neuroprotective effect; Polyethylene glycol 6000 (PubChem CID: 174); Proanthocyanidin; Proanthocyanidin B5 (PubChem CID: 124017); Silicon dioxide (PubChem CID: 24261); Sodium Dodecyl Benzene Sulfonate (PubChem CID: 23662403)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Curcumina / Proantocianidinas / Nanopartículas / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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