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Multiplexed Protein Biomarker Detection with Microfluidic Electrochemical Immunoarrays.
Jones, Abby; Czarnecki, Patricia; Dhanapala, Lasangi; Rusling, James F.
Afiliação
  • Jones A; Department of Chemistry, University of Connecticut, Storrs, CT, USA.
  • Czarnecki P; Department of Chemistry, University of Connecticut, Storrs, CT, USA.
  • Dhanapala L; Department of Chemistry, University of Connecticut, Storrs, CT, USA.
  • Rusling JF; Department of Chemistry, University of Connecticut, Storrs, CT, USA. james.rusling@uconn.edu.
Methods Mol Biol ; 2237: 69-82, 2021.
Article em En | MEDLINE | ID: mdl-33237409
ABSTRACT
Electrochemistry is a multidisciplinary field encompassing the study of analytes in solution for detection and quantification. For the medical field, this brings opportunities to the clinical practice of disease detection through measurements of disease biomarkers. Specifically, panels of biomarkers offer an important future option that can enable physicians' access to blood, saliva, or urine bioassays for screening diseases, as well as monitoring the progression and response to therapy. Here, we describe the simultaneous detection of eight protein cancer biomarkers in a 30-min assay by a microfluidic electrochemical immunoarray.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes Imunológicos / Biomarcadores Tumorais / Análise Serial de Proteínas / Microfluídica / Técnicas Eletroquímicas Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes Imunológicos / Biomarcadores Tumorais / Análise Serial de Proteínas / Microfluídica / Técnicas Eletroquímicas Idioma: En Ano de publicação: 2021 Tipo de documento: Article