Perioperative Chemotherapy for Liver Metastasis of Colorectal Cancer.
Cancers (Basel)
; 12(12)2020 Nov 26.
Article
em En
| MEDLINE
| ID: mdl-33256170
ABSTRACT
The liver is the dominant site of metastasis for patients with colorectal cancer. For those with isolated liver metastases, surgical resection with systemic therapy has led to long-term remission in as high as 80% of patients in well-selected cohorts. This review will focus on how systemic therapy should be integrated with resection of liver metastases; in particular, the use of clinical risk scores based on clinicopathological features that help with patient selection, various approaches to the treatment of micro-metastatic disease (peri-operative versus post-operative chemotherapy), as well as conversion chemotherapy for those with initially upfront unresectable disease will be discussed.
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MEDLINE
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En
Ano de publicação:
2020
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Article