NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV.

Zhao, Bailin; Naila, Tasmin; Lieber, Michael R; Tomkinson, Alan E

Zhao, Bailin; Naila, Tasmin; Lieber, Michael R; Tomkinson, Alan E.

Afiliação

Zhao B; Department of Pathology, Biochemistry and Molecular Biology, Molecular Microbiology and Immunology, and Section of Computational and Molecular Biology, USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, 1441 Eastlake Ave, Rm. 5428, Los Angeles, CA 9008
Naila T; Department of Internal Medicine and Molecular Genetics and Microbiology, and the University of New Mexico Comprehensive Cancer Center, University of New Mexico, 915 Camino de Salud, Albuquerque, NM 87131, USA.
Lieber MR; Department of Pathology, Biochemistry and Molecular Biology, Molecular Microbiology and Immunology, and Section of Computational and Molecular Biology, USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, 1441 Eastlake Ave, Rm. 5428, Los Angeles, CA 9008
Tomkinson AE; Department of Internal Medicine and Molecular Genetics and Microbiology, and the University of New Mexico Comprehensive Cancer Center, University of New Mexico, 915 Camino de Salud, Albuquerque, NM 87131, USA.

Nucleic Acids Res ; 48(22): 12746-12750, 2020 12 16.

Article em En | MEDLINE | ID: mdl-33264406

Assuntos

Adenosina Difosfato Ribose/genética; DNA Ligase Dependente de ATP/genética; DNA/genética; NAD/genética; Monofosfato de Adenosina/genética; Trifosfato de Adenosina/genética; Sequência de Aminoácidos/genética; Quebras de DNA de Cadeia Dupla; Reparo do DNA/genética; Humanos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Adenosina Difosfato Ribose / DNA Ligase Dependente de ATP / NAD Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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