Application of the Bethesda System for Reporting Thyroid Cytopathology in the Pediatric Population.
Am J Clin Pathol
; 155(5): 680-689, 2021 04 26.
Article
em En
| MEDLINE
| ID: mdl-33269383
ABSTRACT
OBJECTIVES:
We aimed to provide the Asian experience with the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) in pediatric thyroid nodules.METHODS:
Consecutive thyroid fine-needle aspirates (patient age, ≤18 years) were retrospectively collected from 7 tertiary centers in 5 Asian countries.RESULTS:
Of 194,364 thyroid aspirates, 0.6% were pediatric cases (mean age, 15.0 years). Among 827 nodules with accessible follow-up, the resection rate and risk of malignancy (ROM) were 36.3% and 59.0%, respectively. Malignant nodules (n = 179) accounted for 59.7% of resected nodules and 21.6% of all thyroid nodules with available follow-up. Compared with the published adult series, pediatric nodules had a higher resection rate and ROM, particularly in the indeterminate categories.CONCLUSIONS:
Our study demonstrates that Asian pediatric thyroid nodules had higher ROM than those from adults. The prototypic outputs of TBSRTC may need to be adjusted in the pediatric population.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Glândula Tireoide
/
Neoplasias da Glândula Tireoide
/
Nódulo da Glândula Tireoide
/
Câncer Papilífero da Tireoide
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article