Neobavaisoflavone Demonstrates Valid Anti-tumor Effects in Non-Small- Cell Lung Cancer by Inhibiting STAT3.

Cai, Xueding; Zhou, Feng; Xie, Xiaona; Zheng, Dandan; Yao, Yulei; Zhao, Chengguang; Huang, Xiaoying; Hu, Ke

Cai, Xueding; Zhou, Feng; Xie, Xiaona; Zheng, Dandan; Yao, Yulei; Zhao, Chengguang; Huang, Xiaoying; Hu, Ke.

Afiliação

Cai X; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Zhangzhidong Road No.99, Wuhan, Hubei 430060,China.
Zhou F; Division of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang 325000,China.
Xie X; Division of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang 325000,China.
Zheng D; Division of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang 325000,China.
Yao Y; Division of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang 325000,China.
Zhao C; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035,China.
Huang X; Division of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang 325000,China.
Hu K; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Zhangzhidong Road No.99, Wuhan, Hubei 430060,China.

Comb Chem High Throughput Screen ; 25(1): 29-37, 2022.

Article em En | MEDLINE | ID: mdl-33280587

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Isoflavonas; Neoplasias Pulmonares; Apoptose; Carcinoma Pulmonar de Células não Pequenas/patologia; Linhagem Celular Tumoral; Proliferação de Células; Humanos; Isoflavonas/farmacologia; Neoplasias Pulmonares/patologia; Fator de Transcrição STAT3/metabolismo; Fator de Transcrição STAT3/farmacologia; Fator de Transcrição STAT3/uso terapêutico

Palavras-chave

NSCLC; Neobavaisoflavone; STAT3; antitumor; apoptosis; pathology.

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Isoflavonas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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