Towards a comprehensive view of 8-oxo-7,8-dihydro-2'-deoxyguanosine: Highlighting the intertwined roles of DNA damage and epigenetics in genomic instability.

Gorini, Francesca; Scala, Giovanni; Cooke, Marcus S; Majello, Barbara; Amente, Stefano

Gorini, Francesca; Scala, Giovanni; Cooke, Marcus S; Majello, Barbara; Amente, Stefano.

Afiliação

Gorini F; Department of Molecular Medicine and Medical Biotechnologies, University of Naples 'Federico II', Naples, Italy.
Scala G; Department of Biology, University of Naples 'Federico II', Naples, Italy.
Cooke MS; Oxidative Stress Group, Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL, USA.
Majello B; Department of Biology, University of Naples 'Federico II', Naples, Italy.
Amente S; Department of Molecular Medicine and Medical Biotechnologies, University of Naples 'Federico II', Naples, Italy. Electronic address: stamente@unina.it.

DNA Repair (Amst) ; 97: 103027, 2021 01.

Article em En | MEDLINE | ID: mdl-33285475

Assuntos

8-Hidroxi-2'-Desoxiguanosina/metabolismo; Dano ao DNA; Epigênese Genética; Instabilidade Genômica; Animais; DNA/metabolismo; Reparo do DNA; Eucariotos/genética; Eucariotos/metabolismo; Humanos; Modelos Genéticos

Palavras-chave

8-oxodG; Base excision repair; Cancer; Double-strand break; Genome instability; Single-Strand break; TOP1-DPC

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Instabilidade Genômica / Epigênese Genética / 8-Hidroxi-2'-Desoxiguanosina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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