Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin.

Bacolla, Albino; Sengupta, Shiladitya; Ye, Zu; Yang, Chunying; Mitra, Joy; De-Paula, Ruth B; Hegde, Muralidhar L; Ahmed, Zamal; Mort, Matthew; Cooper, David N; Mitra, Sankar; Tainer, John A

Bacolla, Albino; Sengupta, Shiladitya; Ye, Zu; Yang, Chunying; Mitra, Joy; De-Paula, Ruth B; Hegde, Muralidhar L; Ahmed, Zamal; Mort, Matthew; Cooper, David N; Mitra, Sankar; Tainer, John A.

Afiliação

Bacolla A; Departments of Cancer Biology and of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Sengupta S; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Ye Z; Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
Yang C; Departments of Cancer Biology and of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Mitra J; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
De-Paula RB; Department of Neurosurgery, Center for Neuroregeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.
Hegde ML; Departments of Cancer Biology and of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Ahmed Z; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Mort M; Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
Cooper DN; Department of Neurosurgery, Center for Neuroregeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.
Mitra S; Departments of Cancer Biology and of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Tainer JA; Institute of Medical Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.

Nucleic Acids Res ; 49(1): 221-243, 2021 01 11.

Article em En | MEDLINE | ID: mdl-33300026

Assuntos

Cromatina/fisiologia; DNA Glicosilases/metabolismo; Reparo do DNA; Processamento de Proteína Pós-Traducional; Acetilação; Animais; Linhagem Celular Tumoral; Núcleo Celular/metabolismo; Cromatina/ultraestrutura; DNA Glicosilases/química; DNA Glicosilases/fisiologia; Reparo do DNA/genética; Conjuntos de Dados como Assunto; Evolução Molecular; Genes de Helmintos; Genes Homeobox; Células HEK293; Proteínas de Helminto/genética; Humanos; Invertebrados/genética; Invertebrados/metabolismo; Lisina/química; Mutação; Proteínas de Neoplasias/metabolismo; Neoplasias/genética; Neoplasias/metabolismo; Neoplasias/mortalidade; Oxirredução; Proteoma; Alinhamento de Sequência; Homologia de Sequência de Aminoácidos; Sítio de Iniciação de Transcrição; Vertebrados/genética; Vertebrados/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Processamento de Proteína Pós-Traducional / DNA Glicosilases / Reparo do DNA Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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