Loss of Fibroblast Growth Factor Receptor 2 (FGFR2) Leads to Defective Bladder Urothelial Regeneration after Cyclophosphamide Injury.

Narla, Sridhar T; Bushnell, Daniel S; Schaefer, Caitlin M; Nouraie, Mehdi; Tometich, Justin T; Hand, Timothy W; Bates, Carlton M

Narla, Sridhar T; Bushnell, Daniel S; Schaefer, Caitlin M; Nouraie, Mehdi; Tometich, Justin T; Hand, Timothy W; Bates, Carlton M.

Afiliação

Narla ST; Division of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Bushnell DS; Division of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Schaefer CM; Division of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Nouraie M; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Tometich JT; Mellon Institute for Pediatric Research, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Infectious Disease Section, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
Hand TW; Mellon Institute for Pediatric Research, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Infectious Disease Section, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
Bates CM; Division of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Division of Nephrology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: batescm@upmc.edu.

Am J Pathol ; 191(4): 631-651, 2021 04.

Article em En | MEDLINE | ID: mdl-33385344

Assuntos

Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/genética; Regeneração/fisiologia; Bexiga Urinária/metabolismo; Urotélio/metabolismo; Animais; Diferenciação Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Ciclofosfamida/farmacologia; Cistite/induzido quimicamente; Cistite/metabolismo; Modelos Animais de Doenças; Camundongos Transgênicos; Músculo Liso/metabolismo; Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/efeitos dos fármacos; Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/metabolismo; Regeneração/efeitos dos fármacos; Regeneração/genética; Risco; Bexiga Urinária/lesões; Bexiga Urinária/patologia; Urotélio/patologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regeneração / Bexiga Urinária / Urotélio / Receptor Tipo 2 de Fator de Crescimento de Fibroblastos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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