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Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI.
Kearney, Katherine J; Butler, Juliet; Posada, Olga M; Wilson, Clare; Heal, Samantha; Ali, Majid; Hardy, Lewis; Ahnström, Josefin; Gailani, David; Foster, Richard; Hethershaw, Emma; Longstaff, Colin; Philippou, Helen.
Afiliação
  • Kearney KJ; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Butler J; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Posada OM; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Wilson C; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Heal S; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Ali M; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Hardy L; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Ahnström J; Faculty of Medicine, Department of Immunology and Inflammation, Imperial College London, Hammersmith Campus, W12 0NN London, United Kingdom.
  • Gailani D; Division of Hematology/Oncology, The Vanderbilt Clinic, Vanderbilt University, Nashville, TN 37232.
  • Foster R; School of Chemistry, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Hethershaw E; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom.
  • Longstaff C; Division of Biotherapeutics, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, EN6 3QG, United Kingdom.
  • Philippou H; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, LS2 9JT Leeds, United Kingdom; h.philippou@leeds.ac.uk.
Proc Natl Acad Sci U S A ; 118(3)2021 01 19.
Article em En | MEDLINE | ID: mdl-33397811
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator IX / Fator XII / Fibrina / Bradicinina / Calicreínas / Trombina Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator IX / Fator XII / Fibrina / Bradicinina / Calicreínas / Trombina Idioma: En Ano de publicação: 2021 Tipo de documento: Article