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Computationally predicted SARS-COV-2 encoded microRNAs target NFKB, JAK/STAT and TGFB signaling pathways.
Aydemir, Merve Nur; Aydemir, Habes Bilal; Korkmaz, Ertan Mahir; Budak, Mahir; Cekin, Nilgun; Pinarbasi, Ergun.
Afiliação
  • Aydemir MN; Department of Molecular Biology and Genetics, Faculty of Science, Sivas Cumhuriyet University, Sivas, Turkey.
  • Aydemir HB; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Gaziosmanpasa University, Tokat, Turkey.
  • Korkmaz EM; Department of Molecular Biology and Genetics, Faculty of Science, Sivas Cumhuriyet University, Sivas, Turkey.
  • Budak M; Department of Molecular Biology and Genetics, Faculty of Science, Sivas Cumhuriyet University, Sivas, Turkey.
  • Cekin N; Sivas Cumhuriyet University, Faculty of Medicine, Department of Medical Biology, 58140 Sivas, Turkey.
  • Pinarbasi E; Sivas Cumhuriyet University, Faculty of Medicine, Department of Medical Biology, 58140 Sivas, Turkey.
Gene Rep ; 22: 101012, 2021 Mar.
Article em En | MEDLINE | ID: mdl-33398248
Palavras-chave
ACE-2, angiotensin-converting enzyme 2; AKT1, AKT serine/threonine kinase 1; BCL2, BCL2 apoptosis regulator; CDK1, cyclin dependent kinase 1; CDKL2, cyclin dependent kinase like 2; COVID19, new type corona virus disease; CTNNB1, catenin beta 1; CXCL1, C-X-C motif chemokine ligand 1; CXCL10, C-X-C motif chemokine ligand 10; CXCL11, C-X-C motif chemokine ligand 11; CXCL16, C-X-C motif chemokine ligand 16; CXCL9, C-X-C motif chemokine ligand 9; E2F1, E2F transcription factor 1; EIF4A1, eukaryotic translation initiation factor 4A1; GRB2, growth factor receptor bound protein 2; HDAC1, histone deacetylase 1; HDAC2, histone deacetylase 2; HDAC3, histone deacetylase 3; HIF1A, hypoxia inducible factor 1 subunit alpha; ICTV, International Committee on Taxonomy of Viruses; IFNGR2, interferon gamma receptor 2; IKBKE, inhibitor of nuclear factor kappa B kinase subunit epsilon; IL10, interleukin 10; IL13, interleukin 13; IL15, interleukin 15; IL16, interleukin 16; IL17A, interleukin 17 A; IL2, interleukin 2; IL21, interleukin 21; IL22, interleukin 22; IL24, interleukin 24; IL25, interleukin 25; IL33, interleukin 33; IL5, interleukin 5; IL7, interleukin 7; IL8, interleukin 8; JAK/STAT; JAK1, Janus kinase 1; JAK2, Janus kinase 2; JARID1A, lysine demethylase 5A; JARID1B, lysine demethylase 5B; JARID1C, lysine demethylase 5C; JARID2, Jumonji and AT-rich interaction domain containing 2; KEGG, Kyoto Encyclopedia of Genes and Genomes; MAPK1, mitogen-activated protein kinase 1; MAPK3, mitogen-activated protein kinase 3; MAPK4, mitogen-activated protein kinase 4; MAPK6, mitogen-activated protein kinase 6; MAPK7, mitogen-activated protein kinase 7; NFKB; NFKB1, nuclear factor kappa B subunit 1; NFKBIE, NFKB inhibitor epsilon; NOS3, nitric oxide synthase 3; PANTHER, protein analysis through evolutionary relationships; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; PTEN, phosphatase and tensin homolog; RB1, RB transcriptional corepressor 1; RHOA, ras homolog family member A; SARS-CoV-2; SARS-CoV-2, severe acute respiratory disease coronavirus type 2; SMAD2, SMAD family member 2; SMAD3, SMAD family member 3; SMAD4, SMAD family member 4; SOCS1, suppressor of cytokine signaling 1; SOCS3, suppressor of cytokine signaling 3; SOCS4, suppressor of cytokine signaling 4; SOCS5, suppressor of cytokine signaling 5; SOCS6, suppressor of cytokine signaling 6; SOS1, SOS Ras/Rac guanine nucleotide exchange factor 1; SP1, Sp1 transcription factor; STAT3, signal transducer and activator of transcription 3; STAT4, signal transducer and activator of transcription 4; STAT5B, signal transducer and activator of transcription 5B; STAT6, signal transducer and activator of transcription 6; SUMO1, small ubiquitin like modifier 1; SUMO2, small ubiquitin like modifier 2; TBP, TATA-box binding protein; TGFB; TGFBR1, transforming growth factor beta receptor 1; TGFBR2, transforming growth factor beta receptor 2; TMPRSS11A, transmembrane serine protease 11A; TMPRSS4, transmembrane serine protease 4; TNFRSF21, TNF receptor superfamily member 21; WHO, World Health Organization; miRNA

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article