A case of eosinophilic esophagitis with autoimmune polyendocrine syndrome type 2, including autoimmune gastritis.
Clin J Gastroenterol
; 14(2): 460-465, 2021 Apr.
Article
em En
| MEDLINE
| ID: mdl-33411318
ABSTRACT
Both eosinophilic esophagitis (EoE) and autoimmune polyendocrine syndrome (APS) are relatively rare diseases in Japan. We herein report a case of EoE with APS in a 67-year-old Japanese man who presented with chest pain and dysphagia. On the basis of endoscopic findings and histological analysis, we diagnosed the patient with EoE along with autoimmune gastritis. Additional serological examinations revealed the presence of Hashimoto's thyroiditis and type 1 diabetes, which led to the final diagnosis of APS. His symptoms did not respond to treatment with a proton-pump inhibitor but improved with topical steroid therapy. This case of coexisting EoE and APS-2 is quite rare and has several implications for the pathogenesis of both conditions.
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MEDLINE
Assunto principal:
Poliendocrinopatias Autoimunes
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Diabetes Mellitus Tipo 2
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Esofagite Eosinofílica
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Gastrite
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article