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Gefitinib initiates sterile inflammation by promoting IL-1ß and HMGB1 release via two distinct mechanisms.
Noguchi, Takuya; Sekiguchi, Yuto; Kudoh, Yuki; Naganuma, Rio; Kagi, Tomohiro; Nishidate, Akiko; Maeda, Kazuhiro; Ishii, Chizuru; Toyama, Takashi; Hirata, Yusuke; Hwang, Gi-Wook; Matsuzawa, Atsushi.
Afiliação
  • Noguchi T; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Sekiguchi Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Kudoh Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Naganuma R; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Kagi T; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Nishidate A; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Maeda K; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Ishii C; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Toyama T; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Hirata Y; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Hwang GW; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Matsuzawa A; Laboratory of Environmental and Health Sciences, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Cell Death Dis ; 12(1): 49, 2021 01 06.
Article em En | MEDLINE | ID: mdl-33414419
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína HMGB1 / Inibidores de Proteínas Quinases / Interleucina-1beta / Gefitinibe / Inflamação Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína HMGB1 / Inibidores de Proteínas Quinases / Interleucina-1beta / Gefitinibe / Inflamação Idioma: En Ano de publicação: 2021 Tipo de documento: Article