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Protriptyline improves spatial memory and reduces oxidative damage by regulating NFκB-BDNF/CREB signaling axis in streptozotocin-induced rat model of Alzheimer's disease.
Tiwari, Virendra; Mishra, Akanksha; Singh, Sonu; Mishra, Sandeep Kumar; Sahu, Kiran Kumari; Kulkarni, Mahesh J; Shukla, Rakesh; Shukla, Shubha.
Afiliação
  • Tiwari V; Division of Neuroscience and Ageing Biology, CSIR-Central Drug Research Institute, Lucknow 226031, U.P., India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Mishra A; Division of Neuroscience and Ageing Biology, CSIR-Central Drug Research Institute, Lucknow 226031, U.P., India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY 01595, USA.
  • Singh S; Division of Neuroscience and Ageing Biology, CSIR-Central Drug Research Institute, Lucknow 226031, U.P., India; Department of Neuroscience, School of Medicine, University of Connecticut (Uconn) Health Center, 263 Farmington Avenue, L-4078, Farmington, CT 06030, USA.
  • Mishra SK; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India; Department of Pharmacology, CSIR-Central Drug Research Institute, Lucknow 226031, U. P, India.
  • Sahu KK; Division of Neuroscience and Ageing Biology, CSIR-Central Drug Research Institute, Lucknow 226031, U.P., India.
  • Parul; Division of Neuroscience and Ageing Biology, CSIR-Central Drug Research Institute, Lucknow 226031, U.P., India.
  • Kulkarni MJ; Proteomics Facility, Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Pune 411008, India.
  • Shukla R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India; Department of Pharmacology, CSIR-Central Drug Research Institute, Lucknow 226031, U. P, India.
  • Shukla S; Division of Neuroscience and Ageing Biology, CSIR-Central Drug Research Institute, Lucknow 226031, U.P., India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: shubha_shukla@cdri.res.in.
Brain Res ; 1754: 147261, 2021 03 01.
Article em En | MEDLINE | ID: mdl-33422534

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protriptilina / Estresse Oxidativo / Doença de Alzheimer / Memória Espacial Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protriptilina / Estresse Oxidativo / Doença de Alzheimer / Memória Espacial Idioma: En Ano de publicação: 2021 Tipo de documento: Article