Cardioprotective potential of amygdalin against angiotensin II induced cardiac hypertrophy, oxidative stress and inflammatory responses through modulation of Nrf2 and NF-&#954;B activation.

Kung, Yen-Lun; Lu, Cheng-You; Badrealam, Khan Fareen; Kuo, Wei-Wen; Shibu, Marthandam Asokan; Day, Cecilia Hsuan; Chen, Ray-Jade; Lu, Shang-Yeh; Padma, Viswanadha Vijaya; Huang, Chih-Yang

Cardioprotective potential of amygdalin against angiotensin II induced cardiac hypertrophy, oxidative stress and inflammatory responses through modulation of Nrf2 and NF-κB activation.

Kung, Yen-Lun; Lu, Cheng-You; Badrealam, Khan Fareen; Kuo, Wei-Wen; Shibu, Marthandam Asokan; Day, Cecilia Hsuan; Chen, Ray-Jade; Lu, Shang-Yeh; Padma, Viswanadha Vijaya; Huang, Chih-Yang.

Afiliação

Kung YL; Integration of Chinese medicine and Modern medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Lu CY; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Badrealam KF; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Kuo WW; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Shibu MA; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan.
Day CH; Ph.D. Program for Biotechnology Industry, China Medical University, Taichung, Taiwan.
Chen RJ; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Lu SY; Department of Nursing, MeiHo University, Pingtung, Taiwan.
Padma VV; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Huang CY; Division of Cardiovascular Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.

Environ Toxicol ; 36(5): 926-934, 2021 May.

Article em En | MEDLINE | ID: mdl-33448586

Assuntos

Amigdalina; Angiotensina II; Amigdalina/farmacologia; Angiotensina II/metabolismo; Animais; Cardiomegalia/induzido quimicamente; Cardiomegalia/prevenção & controle; Simulação de Acoplamento Molecular; Miócitos Cardíacos/metabolismo; Fator 2 Relacionado a NF-E2/genética; Fator 2 Relacionado a NF-E2/metabolismo; NF-kappa B/genética; NF-kappa B/metabolismo; Estresse Oxidativo

Palavras-chave

amygdalin; angiotensin; cardiac hypertrophy; inflammation; oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiotensina II / Amigdalina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

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XML

PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiotensina II / Amigdalina Idioma: En Ano de publicação: 2021 Tipo de documento: Article