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An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.
Cohain, Ariella T; Barrington, William T; Jordan, Daniel M; Beckmann, Noam D; Argmann, Carmen A; Houten, Sander M; Charney, Alexander W; Ermel, Raili; Sukhavasi, Katyayani; Franzen, Oscar; Koplev, Simon; Whatling, Carl; Belbin, Gillian M; Yang, Jialiang; Hao, Ke; Kenny, Eimear E; Tu, Zhidong; Zhu, Jun; Gan, Li-Ming; Do, Ron; Giannarelli, Chiara; Kovacic, Jason C; Ruusalepp, Arno; Lusis, Aldons J; Bjorkegren, Johan L M; Schadt, Eric E.
Afiliação
  • Cohain AT; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Barrington WT; Department of Human Genetics/Medicine, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
  • Jordan DM; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Beckmann ND; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Argmann CA; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Houten SM; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Charney AW; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ermel R; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Sukhavasi K; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Franzen O; Department of Cardiac Surgery, Tartu University Hospital, Tartu, Estonia.
  • Koplev S; Department of Cardiac Surgery, Tartu University Hospital, Tartu, Estonia.
  • Whatling C; Integrated Cardio Metabolic Centre, Department of Medicine, Karolinska Institutet, Karolinska Universitetssjukhuset, Huddinge, Sweden.
  • Belbin GM; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Yang J; Translational Science, Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Hao K; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Kenny EE; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Tu Z; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zhu J; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Gan LM; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Do R; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Giannarelli C; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Kovacic JC; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ruusalepp A; Early Clinical Development, Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Lusis AJ; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Bjorkegren JLM; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Schadt EE; Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Nat Commun ; 12(1): 547, 2021 01 22.
Article em En | MEDLINE | ID: mdl-33483510
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Doença da Artéria Coronariana / Diabetes Mellitus Tipo 2 / Metabolismo dos Lipídeos / Glucose / Modelos Biológicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Doença da Artéria Coronariana / Diabetes Mellitus Tipo 2 / Metabolismo dos Lipídeos / Glucose / Modelos Biológicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article