Structure-Activity Relationship of Neuroactive Steroids, Midazolam, and Perampanel Toward Mitigating Tetramine-Triggered Activity in Murine Hippocampal Neuronal Networks.

Antrobus, Shane; Pressly, Brandon; Nik, Atefeh Mousavi; Wulff, Heike; Pessah, Isaac N

Antrobus, Shane; Pressly, Brandon; Nik, Atefeh Mousavi; Wulff, Heike; Pessah, Isaac N.

Afiliação

Antrobus S; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California 95616, USA.
Pressly B; Department of Pharmacology, School of Medicine, University of California, Davis, Davis, California 95616, USA.
Nik AM; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California 95616, USA.
Wulff H; Department of Pharmacology, School of Medicine, University of California, Davis, Davis, California 95616, USA.
Pessah IN; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California 95616, USA.

Toxicol Sci ; 180(2): 325-341, 2021 04 12.

Article em En | MEDLINE | ID: mdl-33483729

Assuntos

Neuroesteroides; Animais; Hidrocarbonetos Aromáticos com Pontes; Hipocampo/metabolismo; Camundongos; Midazolam/farmacologia; Nitrilas; Piridonas; Receptores de GABA-A/metabolismo; Relação Estrutura-Atividade

Palavras-chave

acute neurotoxicity; benzodiazepines; calcium signaling; neuroactive steroids; neuronal networks; pesticides; seizure; tetramine

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neuroesteroides Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neuroesteroides Idioma: En Ano de publicação: 2021 Tipo de documento: Article